Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A synthetic peptide of human BCL2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 596 |
Swiss Prot: | P10415 |
Synonyms: | Bcl-2;PPP1R50 |
Purification: | Affinity purification |
Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. |
Caculated MW: | 22kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100 |
Reacitivity: | Human |