Species: | Rabbit |
Applications: | WB IHC ELISA IP IF |
Immunogen Range: | A synthetic phosphopeptide corresponding to residues surrounding S536 of human RELA |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5970 |
Swiss Prot: | Q04206 |
Synonyms: | MGC131774, NFKB3, p65 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. |
Caculated MW: | 65 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:500 IHC 1:100-1:500 IF 1:100-1:500 |
Reacitivity: | Chicken, Cow, Dog, Horse, Human, Mouse, Rat |