ARP5430P-21S [Polyclonal Antibody]
Phospho-POLR2A-Ser2/5 Rabbit Polyclonal Antibody (IP Preferred)
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Species:   Rabbit
Applications:   WB IP
Immunogen Range:   /
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   5430
Swiss Prot:   P24928
Synonyms:   MGC75453, POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq
Caculated MW:   250 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   /
For research use only. Not intended for diagnostic or therapeutic use!
Additional information