Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human U3 small nucleolar ribonucleoprotein protein IMP3 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 55272 |
Swiss Prot: | |
Synonyms: | BRMS2, C15orf12, Chromosome 15 open reading frame 12, imp3, IMP3_HUMAN, Mitochondrial ribosomal protein S4, MRPS4, U3 small nucleolar ribonucleoprotein protein imp3, U3 snoRNP protein 3 homolog, U3 snoRNP protein imp3. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Imp3, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |