YRP09586-01 [Polyclonal Antibody]
SHARPIN Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human SHARPIN
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:  
Swiss Prot:  
Synonyms:   hSIPL1, Shank associated RH domain interacting protein, SHANK associated RH domain interactor, Shank interacting protein like 1, Shank-associated RH domain-interacting protein, Shank-interacting protein-like 1, Sharpin, SHRPN_HUMAN, SIPL1, DKFZp434N1923.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   SHARPIN is a 387 amino acid protein that localizes to the cytoplasm and contains one RanBP2-type zinc finger. Expressed at high levels in placenta and skeletal muscle and present at lower levels in colon, brain, heart, liver, kidney, lung, thymus and small intestine, SHARPIN interacts with Shank 1 and is thought to play a role in the control of inflammatory responses and in the overall development of the immune system. SHARPIN exists as three alternatively spliced isoforms and shares 73% sequence identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding SHARPIN maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information