YRP10415-01
[Polyclonal Antibody]
Chemerin Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC IF |
| Immunogen Range: |
KLH conjugated synthetic peptide derived from rat chemerin |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
297073 |
| Swiss Prot: |
|
| Synonyms: |
Rarres2, TIG2, tazarotene induced gene 2, Retinoic acid receptor responder protein 2, Tazarotene-induced gene 2 protein, RAR-responsive protein TIG2, Chemerin. |
| Purification: |
Purified by Protein A. |
| Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: |
Chemerin, also known as retinoic acid receptor responder 2 (RARRES2) and tazarotene induced gene 2 (TIG2), is a chemoattractant protein for cells expressing G-protein-linked receptor chemokine-like receptor 1 (CMKLR1, ChemR23 or GPCR-DEZ). The protein is synthesized as a secreted precursor, prochemerin (18 kDa), which is poorly active. Upon proteolytic removal of the last six amino acids, prochemerin is converted into mature active chemerin (15-16 kDa) that acts as a strong and highly specific agonist of its receptor CMKLR1. Chemerin is a newly described adipokine with effects on adipocyte differnetiation and metabolism. |
| Caculated MW: |
/ |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
| Reacitivity: |
Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!