YRP09468-01 [Polyclonal Antibody]
SYNC Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human SYNC/Syncoilin
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:  
Swiss Prot:  
Synonyms:   Intermediate filament protein syncoilin, SYNC, SYNC1, SYNCI_HUMAN, Syncoilin, Syncoilin intermediate filament 1, Syncoilin-1.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Syncoilin (SYNC) is a 483 amino acid member of the intermediate filament family. Localized to the perinuclear region of cytoplasm, Syncoilin interacts with Alpha-Dystrobrevin and Desmin. Syncoilin links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle, and is therefore found at high levels in cardiac and skeletal muscle. Syncoilin is upregulated at the sarcolemma in individuals with various forms of neuromuscular disease. The gene that encodes Syncoilin maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information