YRP09467-01 [Polyclonal Antibody]
LAGY Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human HOPX/LAGY
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   84525
Swiss Prot:  
Synonyms:   SMAP31, CAMEO, HOD, Homeodomain-only protein, HOP, HOP homeobox, HOP_HUMAN, HOPX, LAGY, Lung cancer-associated Y protein, NECC1, Not expressed in choriocarcinoma clone 1, Not expressed in choriocarcinoma protein 1, Odd homeobox protein 1, TOTO.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information