YRP09467-01
[Polyclonal Antibody]
LAGY Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
IHC IF |
Immunogen Range: |
KLH conjugated synthetic peptide derived from human HOPX/LAGY |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
84525 |
Swiss Prot: |
|
Synonyms: |
SMAP31, CAMEO, HOD, Homeodomain-only protein, HOP, HOP homeobox, HOP_HUMAN, HOPX, LAGY, Lung cancer-associated Y protein, NECC1, Not expressed in choriocarcinoma clone 1, Not expressed in choriocarcinoma protein 1, Odd homeobox protein 1, TOTO. |
Purification: |
Purified by Protein A. |
Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: |
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. |
Caculated MW: |
/ |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!