
| Species: | Rabbit |
| Applications: | WB FC IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from human IGSF6 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 10261 |
| Swiss Prot: | O95976 |
| Synonyms: | DORA, Immunoglobulin superfamily member 6, IgSF6, Protein DORA |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF6 (immunoglobulin superfamily, member 6), also known as DORA, is a novel 241 amino acid single-pass type I membrane protein that contains one Ig-like C2-type (immunoglobulin-like) domain. Expressed in spleen, dendritic cells, peripheral blood lymphocytes and lymph node, IGSF6 is induced by TNF?and GM-CSF in dendritic cells and downregulated by ionomycin and PMA in monocytes. IGSF6 may function as a co-receptor in the antigen uptake complex or dendritic cell recirculation and is encoded by a gene located on human chromosome 16p12.2, a locus associated with inflammatory bowel disease. |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100 |
| Reacitivity: | Human |