YRP09049-01
[Polyclonal Antibody]
TRPM7 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC IF |
| Immunogen Range: |
KLH conjugated synthetic peptide derived from human TRPM7 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
54822 |
| Swiss Prot: |
Q96QT4 |
| Synonyms: |
CHAK, CHAK1, ALSPDC, LTRPC7, LTrpC-7, TRP-PLIK, Transient receptor potential cation channel subfamily M member 7, Channel-kinase 1, Long transient receptor potential channel 7, TRPM7 |
| Purification: |
Purified by Protein A. |
| Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: |
Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). |
| Caculated MW: |
/ |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!