YRP08874-01
[Polyclonal Antibody]
IP3 Receptor Rabbit Polyclonal Antibody
www.yhsbio.com
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DATASHEET
Species: |
Rabbit |
Applications: |
IHC IF |
Immunogen Range: |
KLH conjugated synthetic peptide derived from human IP3 Receptor |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
3708 |
Swiss Prot: |
Q14643 |
Synonyms: |
ACV, CLA4, IP3R, IP3R1, SCA15, SCA16, SCA29, INSP3R1, PPP1R94, Inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor isoform 1, IP3R 1, Type 1 inositol 1,4,5-trisphosphate receptor, Type 1 InsP3 receptor, ITPR1 |
Purification: |
Purified by Protein A. |
Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: |
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity). |
Caculated MW: |
/ |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!