YRP08557-01 [Polyclonal Antibody]
XDH Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human Xanthine Oxidase/Xanthine
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   7498
Swiss Prot:  
Synonyms:   Xanthine dehydrogenase, Xanthine dehydrogenase/oxidase, Xanthine oxidase, Xanthine oxidoreductase, XD, XDH, XDH_HUMAN, xdha, XO, xor.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).Involvement in disease;Defects in XDH are the cause of xanthinuria type 1 (XU1) . Xanthinuria is characterized by excretion of very large amounts of xanthine in the urine and a tendency to form xanthine stones. Uric acid is strikingly diminished in serum and urine. XU1 is due to isolated xanthine dehydrogenase. XU1 patients can metabolize allopurinol.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information