YRP08542-01 [Polyclonal Antibody]
Thymidylate synthase Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human Thymidylate synthase/TS
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   6916
Swiss Prot:  
Synonyms:   d TMP synthase, EC 2.1.1.45, HsT422, MGC88736, Thymidylate synthase, thymidylate synthetase, TMS, TS, TSase, TYMS, TYMS protein, Tyms thymidylate synthetase, TYSY_HUMAN .
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information