YRP08497-01 [Polyclonal Antibody]
FBXO18 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human FBXO18
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   84893
Swiss Prot:  
Synonyms:   Fbx18, FLJ14590, MGC131916, MGC141935, MGC141937, F box DNA helicase 1, F box only protein 18, F box protein, helicase, 18, F-box only protein 18, F-box DNA helicase 1, FBH1, FBX18_HUMAN.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   FBXO18 belongs to the F-box protein family, whose members share the F-box, an approximately 40 amino acid motif. It has both DNA-dependent ATPase and DNA unwinding activities.FBXO18 is a 1,043 amino acid protein encoded by the human gene FBXO18. FBXO18 belongs to the helicase family (UvrD subfamily) and contains one F-box domain. This nuclear protein is a DNA-dependent ATPase that unwinds double-stranded DNA in a 3' to 5' direction. FBXO18 also recognizes and binds to a variety of phosphorylated proteins and promotes their ubiquitination and degradation. It also interacts with Skp1 in the SCF E3 ubiquitin ligase complex consisting of Skp1, CUL-1, Rbx1 and FBXO18.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information