Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human FBXL3 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 26224 |
Swiss Prot: | |
Synonyms: | F box and leucine rich repeat protein 3, F box and leucine rich repeat protein 3A, F box protein Fbl3a, F-box and leucine-rich repeat protein 3A, F-box/LRR-repeat protein 3, F-box/LRR-repeat protein 3A, FBL3, FBL3A, Fbxl3, FBXL3_HUMAN, FBXL3A. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |