YRP08420-01 [Polyclonal Antibody]
HEATR7B2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human HEATR7B2
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:  
Swiss Prot:  
Synonyms:   DKFZp781F0822, FLJ40243, HEAT repeat family member 7B2, HEAT repeat-containing protein 7B2, Heatr7b2, HTRB2_HUMAN, RGD1305413, XVHEAT repeat family member 7B2.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   HEAT repeats form rod-like helical structures that are involved in intracellular transport. HEATR7B2 (HEAT repeat-containing protein 7B2) is a 1,585 amino acid protein that contains fifteen HEAT repeats. Existing as two alternatively spliced isoforms, the gene encoding HEATR7B2 maps to human chromosome 5p13.1 and mouse chromosome 15 A1. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Cockayne syndrome is associated with chromosome 5 through the ERCC8 gene and familial adenomatous polyposis via the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information