Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human ROCK1 around the phosphorylation site of Thr455+Ser456 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 6647 |
Swiss Prot: | |
Synonyms: | p-ROCK1(Thr455/Ser456), p160 ROCK1, p160ROCK, Renal carcinoma antigen NY REN 35, Rho associated coiled coil containing protein kinase 1, Rho associated protein kinase 1, Rho-associated coiled-coil containing protein kinase 1, ROCK1_HUMAN. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008] |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |