YRP07984-01
[Polyclonal Antibody]
BTBD7 Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
IHC IF |
Immunogen Range: |
KLH conjugated synthetic peptide derived from human BTBD7 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
55727 |
Swiss Prot: |
Q9P203 |
Synonyms: |
FUP1, BTB/POZ domain-containing protein 7, BTBD7, KIAA1525 |
Purification: |
Purified by Protein A. |
Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: |
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity). |
Caculated MW: |
/ |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!