Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human PTOP |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 65057 |
Swiss Prot: | |
Synonyms: | PIP1, Acd, ACD_HUMAN, Adrenocortical dysplasia protein homolog, POT1 and TIN2 organizing protein, POT1 and TIN2-interacting protein, TIN2 interacting protein 1, TINT1, TPP1. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | This gene encodes a protein that is involved in telomerefunction. This protein is one of six core proteins in thetelosome/shelterin telomeric complex, which functions to maintaintelomere length and to protect telomere ends. Through itsinteraction with other components, this protein plays a key role inthe assembly and stabilization of this complex, and it mediates theaccess of telomerase to the telomere. Multiple transcript variantsencoding different isoforms have been found for this gene. Thisgene, which is also referred to as TPP1, is distinct from theunrelated TPP1 gene on chromosome 11, which encodestripeptidyl-peptidase I. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |