Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human DUSP2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 1844 |
Swiss Prot: | |
Synonyms: | Dual specicity phosphatase 2, Dual specicity protein phosphatase 2, Dual specicity protein phosphatase PAC 1, DUSP 2, PAC 1, PAC1, Serine/threonine specic protein phosphatase, DUS2_HUMAN. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | DUSP2 is a dual-specific thr/tyr phosphatase that is a physiologically relevant MAP kinase phosphatase. The gene is located on 2q11.2-q11 and contains 4 exons that span approximately 2.3kb. Under specific stress conditions, p53 regulates transcription of PAC1 through a new p53-binding site, and that PAC1 is necessary and sufficient for p53-mediated apoptosis. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |