Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human KLHL20 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 27252 |
Swiss Prot: | |
Synonyms: | Kelch like ECT2 interacting protein, Kelch like protein 20, Kelch like protein X, Kelch mot containing protein, Kelch-like ECT2-interacting protein, Kelch-like protein 20, Kelch-like protein X, KHLHX, KLEIP, KLH20_HUMAN, KLHL20, KLHLX, RP3-383J4.3. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |