YRP07125-01 [Polyclonal Antibody]
Sulfite oxidase Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human Sulfite oxidase/SUOX
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   6821
Swiss Prot:  
Synonyms:   SO, EC 1.8.3.1, mitochondrial, Sulfite oxidase, Sulfite oxidase mitochondrial, Sulfite oxidase, mitochondrial precursor, Suox, SUOX_HUMAN.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Sulfite oxidase (SO), a homodimeric protein that localizes to the intermembrane space of mitochondria, catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Genetic deficiency of SO contributes to neurological abnormalities and often leads to death at an early age. Mutation of Arginine 160 in humans decreases the intramolecular electron transfer (IET) rate, which contributes to the fatality of this genetic disorder. Also, the tyrosine 343 residue in humans plays an important role in both substrate binding and oxidation of sulfite by SO. The human SO gene maps to chromosome 12, and shows high expression in liver, kidney, skeletal muscle, heart, placenta and brain.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information