Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human FEM 1B |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 10116 |
Swiss Prot: | Q9UK73 |
Synonyms: | F1AA, F1A-ALPHA, FEM1-beta, Protein fem-1 homolog B, FEM1b, Fem-1-like death receptor-binding protein alpha, Fem-1-like in apoptotic pathway protein alpha, KIAA0396 |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |