YRP07115-01 [Polyclonal Antibody]
DOCK1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human DOCK1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1793
Swiss Prot:  
Synonyms:   180 kDa protein downstream of CRK, Ced5, Dedicator of Cytokinesis 1, Dedicator of cytokinesis protein 1, DOCK 1, DOCK-1, DOCK 180, DOCK1, DOCK1_HUMAN, DOCK180.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information