YRP07017-01
[Polyclonal Antibody]
SPANX Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
IHC IF |
Immunogen Range: |
KLH conjugated synthetic peptide derived from human SPANXA |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
30014 |
Swiss Prot: |
Q9NS26 |
Synonyms: |
NAP-X, SPANX, CT11.1, SPAN-X, SPAN-Xa, SPAN-Xb, SPANX-A, Sperm protein associated with the nucleus on the X chromosome A, Cancer/testis antigen 11.1, Nuclear-associated protein SPAN-Xa, SPANX family member A, SPANXA1, SPANXA |
Purification: |
Purified by Protein A. |
Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: |
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008] |
Caculated MW: |
/ |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!