YRP06600-01 [Polyclonal Antibody]
CENPB Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human CENPB
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1059
Swiss Prot:  
Synonyms:   CENP B, CENP-B, centromere autoantigen B, Centromere protein B, Major centromere autoantigen B, CENPB_HUMAN.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   This gene product is a highly conserved protein associated with the centromere. It is a DNA-binding protein containing a helix loop helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17 bp sequence (CENPB box) in the centromeric satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere . (referenced from Entrez Gene)
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information