Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human ARH/LDL receptor adaptor protein |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 26119 |
Swiss Prot: | |
Synonyms: | ARH, ARH GENE, ARH_HUMAN, ARH1, ARH2, Autosomal recessive hypercholesterolemia protein, FHCB1, FHCB2, LDL receptor adaptor protein, Ldlrap1, Low density lipoprotein receptor adapter protein 1. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |