Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human Acylglycerol Kinase |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 55750 |
Swiss Prot: | Q53H12 |
Synonyms: | MULK, CATC5, CTRCT38, MTDPS10, Acylglycerol kinase, mitochondrial, hAGK, Multiple substrate lipid kinase, HsMuLK, Multi-substrate lipid kinase, AGK |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |