YRP06117-01 [Polyclonal Antibody]
ST5 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human ST5/DENND2B
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   6764
Swiss Prot:  
Synonyms:   DENND2B, DENN domain containing protein 2B, HeLa tumor suppression 1, DENN domain-containing protein 2B, DENN/MADD domain containing 2B, DENND2B, HTS1, p126, ST 5, ST5, ST5_HUMAN, Suppression of tumorigenicity 5, Suppression of tumorigenicity 5 protein.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008].
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information