YRP06025-01 [Polyclonal Antibody]
ACVRL1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human ALK1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   94
Swiss Prot:   P37023
Synonyms:   HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, TSR-I, ACVRLK1, Serine/threonine-protein kinase receptor R3, Activin receptor-like kinase 1, TGF-B superfamily receptor type I, ACVRL1
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information