Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human ELMO. |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 9844 |
Swiss Prot: | |
Synonyms: | CED 12, Ced 12 homolog 1, Ced 12 homolog, CED12, Ced12 homolog 1, Ced12 homolog, ELMO 1, Engulfment and cell motility 1, Engulfment and cell motility protein 1, KIAA0281, ELMO1_HUMAN. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | ELMO1 is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. ELMO1 acts in association with DOCK1 and CRK and was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. It is belived to enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |