Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human MAD2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 4601 |
Swiss Prot: | |
Synonyms: | HSMAD2, Human mitotic feedback control protein Madp2 homolog mRNA complete cds, MAD 2, MAD2 like 1, MAD2 mitotic arrest deficient like 1, MAD2B, MAD2L1, Mitotic arrest deficient 2, Mitotic spindle assembly checkpoint protein MAD2A, REV7, MD2L1_HUMAN . |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | MAD2 is a non-essential gene that encodes a component of the spindle checkpoint. The spindle checkpoint delays the onset of anaphase in cells with defects in mitotic spindle assembly or in the attachment of chromosomes to the spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |