YRP05580P-01 [Polyclonal Antibody]
Phospho-AMPK alpha 2 (Ser173) Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic phosphopeptide derived from human PRKAA2 around the phosphorylation site of Ser173
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   5563
Swiss Prot:  
Synonyms:   AMPK alpha 2 phospho Ser173, AMPK alpha 2 phospho S173, PRKAA2phospho S173, p-AMPK alpha 2 Ser173, p-AMPK alpha 2 S173, AMPK 2, AMPK2, AMPKalpha2, PRKAA 2, PRKAA, PRKAA2, Protein kinase AMP activated alpha 2 catalytic subunit.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information