Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human CYP7B1 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 9420 |
Swiss Prot: | |
Synonyms: | 25 hydroxycholesterol 7 alpha hydroxylase, CP7B, Cytochrome P450 7B1, Cytochrome P450 family 7 subfamily B polypeptide 1, Cytochrome P450 subfamily VIIB polypeptide 1, Oxysterol 7alpha hydroxylase, CP7B1_HUMAN. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | The CYP7B1 protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme is likely to play a minor role in total bile acid synthesis, and may also be involved in the development of neurosteroid metabolism, atherosclerosis and sex hormone synthesis, and is a member of the cytochrome P450 superfamily of enzymes. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |