YRP00919-01 [Polyclonal Antibody]
TACR3 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human TACR3
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   6870
Swiss Prot:  
Synonyms:   MGC148060, MGC148061, Neurokinin B receptor, Neuromedin K Receptor, Neuromedin-K receptor, NK 3 receptor, NK-3 receptor, NK-3R, NK3 receptor, NK3R, NK3R_HUMAN, NK 3R, NK3 receptor, NK3R, NKR, TAC 3R, TAC3R, TAC3RL, Tachykinin receptor 3, TACR 3, TACR3.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information