
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from human HSJ2/DNAJB6 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 10049 |
| Swiss Prot: | |
| Synonyms: | DJ4, DnaJ, DNAJ B6, DnaJ homolog subfamily B member 6, DNAJB6, DNJB6_HUMAN, Heat shock protein J2, HHDJ1, HSJ-2, HSJ2, MRJ, MSJ-1, MSJ1. |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Reduces huntingtin aggregation associated with HD. Also reduces cellular toxicity and caspase-3 activity. |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
| Reacitivity: | Human, Mouse, Rat |