
| Species: | Rabbit |
| Applications: | FC IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from rat CD45 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 24699 |
| Swiss Prot: | P04157 |
| Synonyms: | Lca, RT7, CD45, L-CA, T200, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, Ptprc |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100 |
| Reacitivity: | Rat |
