YRP04824-01 [Polyclonal Antibody]
CD45 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   FC IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from rat CD45
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   24699
Swiss Prot:   P04157
Synonyms:   Lca, RT7, CD45, L-CA, T200, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, Ptprc
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   IHC 1:100-1:500
IF 1:50-1:200
FC 1:20-1:100
Reacitivity:   Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information