YRP04312-01
[Polyclonal Antibody]
beta 2 Defensin Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC IF |
| Immunogen Range: |
KLH conjugated synthetic peptide derived from human beta 2 Defensin |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
1673 |
| Swiss Prot: |
O15263 |
| Synonyms: |
BD-2, SAP1, DEFB2, DEFB4, HBD-2, DEFB-2, DEFB12, Beta-defensin 4A, Beta-defensin 2, Defensin, beta 2, Skin-antimicrobial peptide 1, DEFB4A |
| Purification: |
Purified by Protein A. |
| Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: |
Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways |
| Caculated MW: |
/ |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!