YRP04000-01 [Polyclonal Antibody]
SLC16A7/MCT2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human SLC16A7
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   9194
Swiss Prot:  
Synonyms:   MCT 2, MCT, Monocarboxylate transporter 2, MonocarboxylateTransporter 2, MOT2, MOT2_HUMAN, SLC16A7, Solute carrier family 16 member 7, Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters (MCTs) mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate (summary by Lin et al., 1998 [PubMed 9786900]).[supplied by OMIM, Feb 2011].
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information