
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from human CDC34B |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 283337 |
| Swiss Prot: | |
| Synonyms: | CDC34B, E2 CDC34B, UBE2R2, Ubiquitin carrier protein R2, Ubiquitin conjugating enzyme E2 CDC34B, Ubiquitin conjugating enzyme E2 R2, Ubiquitin conjugating enzyme E2R 2, Ubiquitin conjugating enzyme UBC3B, Ubiquitin protein ligase R2. |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | UBC3B is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
| Reacitivity: | Human, Mouse, Rat |