YRP03670-01 [Polyclonal Antibody]
Caspase-7 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human Caspase-7
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   840
Swiss Prot:  
Synonyms:   Apoptosis related cysteine peptidase, Apoptosis Related Cysteine Protease, Apoptotic Protease MCH3, CASP 7, CASP7, Caspase7, Caspase 7, CMH 1, CMH1, ICE LAP3, ICE like Apoptotic Protease 3, MCH3.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].The antibody should recognize both pro-form and p20 cleaved-form. The antibody does not cross-react with other Caspase family members.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information