Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human srGAP3 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 9901 |
Swiss Prot: | |
Synonyms: | ARHGAP 14, ARHGAP14, Gbi, ME GAP, MEGAP, Mental disorder associated GAP, Rho GTPase activating protein 14, SLIT ROBO Rho GTPase activating protein 3, srGAP 2, srGAP 3, srGAP2, SRGP 2, SRGP2, WAVE associated Rac GTPase activating protein, WRP. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | srGAP3 (SLIT ROBO Rho GTPase-activating protein 3) is a GTPase activating protein (GAP) for the small G protein Rac. It has a putative role in attenuating Rac1 signalling in neurons. srGAP3 is thought to act downstream of the Slit-Robo pathway, which regulates neuronal migration and axonal branching, and play an important role in axonal regeneration after axotomy. It also plays a putative role in severe mental retardation. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |