YRP03626-01 [Polyclonal Antibody]
eIF4E Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human eIF4E
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1977
Swiss Prot:  
Synonyms:   E4F, e-4E, e 4E, CBP, e 4F 25 kDa subunit, CBP, e 4E, e 4F 25 kDa subunit, E 4F, E4E1, E4EL1, E4F, Eukaryotic Translation Initiation Factor 4 E, Eukaryotic translation initiation factor 4E like 1, Messanger RNA Cap Binding Protein e 4E.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information