YRP03429P-01 [Polyclonal Antibody]
Phospho-TLK1(Ser695) Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic phosphopeptide derived from human TLK1 around the phosphorylation site of Ser695
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   9874
Swiss Prot:  
Synonyms:   PKU beta, serine threonine protein kinase, Serine/threonine protein kinase tousled like 1, TLK1, Tousled like kinase 1.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   TLK1 is a nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly. TLK1 is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information