YRP00765-01 [Polyclonal Antibody]
Lpin1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from mouse Lpin 1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   14245
Swiss Prot:   Q91ZP3
Synonyms:   fld, Lipin1, Kiaa0188, mKIAA0188, 4631420P06, Phosphatidate phosphatase LPIN1, Fatty liver dystrophy protein, Lipin-1, Lpin1
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information