Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of Tyr759 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5336 |
Swiss Prot: | |
Synonyms: | PLC 2, PLC gamma 2, PLC IV, PLCG2, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2, EC 3.1.4.11, Phosphoinositide phospholipase C, Phospholipase C gamma 2, Phospholipase C, gamma 2 phosphatidylinositol specic, PLCG2_HUMAN. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011]. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |