YRP03125P-01
[Polyclonal Antibody]
Phospho-Cyclin E (Thr395) Rabbit Polyclonal Antibody
www.yhsbio.com
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support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | KLH conjugated synthetic phosphopeptide derived from human Cyclin E around the phosphorylation site of Thr395 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 898 |
| Swiss Prot: | |
| Synonyms: | Cyclin E1 phospho T395, p-Cyclin E1 phospho T395, Cyclin E1 Thr395, CCNE 1, CCNE;CCNE1;Cyclin E1 antibody Cyclin Es;Cyclin Et;CyclinE, G1/S specic cyclin E, CCNE1_HUMAN. |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers. |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information