YRP02786-01 [Polyclonal Antibody]
CACNA1G Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   FC IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human CACNA1G/Cav31
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   8913
Swiss Prot:   O43497
Synonyms:   NBR13, Cav3.1, Ca(V)T.1, Voltage-dependent T-type calcium channel subunit alpha-1G, Cav3.1c, Voltage-gated calcium channel subunit alpha Cav3.1, CACNA1G, KIAA1123
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   IHC 1:100-1:500
IF 1:50-1:200
FC 1:20-1:100
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information