YRP02743-01
[Polyclonal Antibody]
FANCD2 Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
IHC IF |
Immunogen Range: |
KLH conjugated synthetic peptide derived from human FANCD2 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
2177 |
Swiss Prot: |
|
Synonyms: |
FA 4, FA D2, FA4, FAC D2, FACD 2, FACD, FACD2, FAD, FAD2, FANC D2, FANCD 2, FANCD, Protein FACD2, Type 4 Fanconi pancytopenia, FACD2_HUMAN, Fanconi anemia group D2 protein, Protein FACD2. |
Purification: |
Purified by Protein A. |
Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: |
Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation.DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein. |
Caculated MW: |
/ |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!