YRP02691-01
[Polyclonal Antibody]
DKK3 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB FC IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from human DKK3 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 27122 |
| Swiss Prot: | Q9UBP4 |
| Synonyms: | RIG, REIC, Dickkopf-related protein 3, Dickkopf-3, Dkk-3, hDkk-3, DKK3, UNQ258/PRO295 |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100 |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
